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It has been known that excess energy is stored in fat cells, which signal these levels to the brain. Now, scientists have discovered that deleting the clock gene Arntl in fat cells leads to obesity in mice, and also causes a change in the timing of their normal eating schedule...

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Buy generic Femara online without prescription

Femara medicine online

Buy medicine Femara by online form and preparation's action mechanism

Femara covers to antitumor nonsteroid drugs as a specific inhibitor of the aromatase enzyme. One tablet contain Letrozole 2.5 mg. Competitively binding to the subunit of the enzyme aromatase, involved in the synthesis of estrogens, preparation eliminates the stimulating effect of the latter on tumor growth, promotes suppression of tumor growth. With the common form of breast cancer in the post menopausal period, the daily use of remedy leads to a decrease in estradiol, estrone sulfate and estrone in the blood by 75-95%. At the same time, these women do not change the level of androstenedione. That is, the blockade of the biosynthesis of estrogens does not entail the accumulation of androgens, which are precursors of estrogens. Also, the concentrations of luteinizing and follicle-stimulating hormones and thyroid hormones do not change. People must better order Femara online. The drug does not affect the synthesis of steroid hormones in the adrenal glands, so there is no need for correction of glucocorticoids and mineral corticoids.

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Cheap Femara medication without a prescription main use and contraindications

Indications for Femara online are:

  • early stages of breast cancer, cells of which have receptors for hormones, in post menopausal woman, as adjuvant therapy;
  • common hormone-dependent forms of breast cancer in postmenopausal women (first-line therapy);
  • common forms of breast cancer in post menopause women (natural or induced artificially) who received previous therapy with anti estrogens.

There is a good chance to order Femara online overnight no rx. Contraindications are very different:

  • endocrine status characteristic of the reproductive period;
  • pregnancy;
  • the period of lactation (breastfeeding);
  • children and adolescence under 18;
  • hypersensitivity to Letrozole.

There is no information on the use of the preparation in patients with creatinine clearance less than 10 ml/min. Before the appointment, such patients should carefully weigh the relationship between the potential risk and the expected effect of treatment.

Recommended dosage in order to buy tablets of Femara without prescription by pharmacy overnight delivery

For adults, the recommended dose of the preparation of Femara generic is 2.5 mg 1 time / day, daily for a long time. As an extended adjuvant therapy treatment should last for 5 years (no longer than 5 years). If signs of disease progression appear, the use of remedy should be discontinued. In elderly people, correction of the dose is not required. It is a good offer to buy Femara by on-line form. In patients with impaired hepatic and / or renal function, dose adjustment is not required. Nevertheless, for severe violations of the liver, people should be under constant supervision.

Order preparation Femara and concurrent reactions

As a rule, Femara side effects were mild or moderate and mainly associated with suppression of the synthesis of estrogens:

  • digestive system: often - vomiting, indigestion, constipation, diarrhea; sometimes - abdominal pain, stomatitis, dry mouth, increased activity of hepatic enzymes;
  • nervous system: headache, dizziness, depression, anxiety, nervousness, irritability, drowsiness, insomnia, memory impairment, paresthesia, hypoesthesia, eating disorders, episodes of cerebral circulation disorders;
  • hematopoiesis system: sometimes – leukopenia;
  • cardiovascular system: palpitation, tachycardia, thrombophlebitis of the superficial and deep veins, increased blood pressure, coronary artery disease (angina, myocardial infarction, heart failure), thromboembolism, embolism of the pulmonary artery, thrombosis of the arteries, stroke;
  • respiratory system: shortness of breath, cough;
  • dermatological reactions: alopecia, excessive sweating, skin rash (including erythematous, maculopapular, vesicular rash, psoriasis-like rashes), urticaria, itchy skin, dry skin, angioedema, anaphylactic reactions;
  • muscular skeletal system: arthralgia; often - bone pain, osteoporosis, myalgia, bone fractures, arthritis;
  • the senses: sometimes - cataract, blurred vision, eye irritation, a violation of taste;
  • reproductive system: sometimes - vaginal bleeding, vaginal dryness, vaginal discharge, pain in the mammary glands;
  • other: paroxysmal sensations of heat (hot flashes), increased fatigue, asthenia, malaise, peripheral edema, weight gain, hypercholesterolemia, anorexia, increased appetite.

Overdose of cheap drug Femara by using no prescription

There are separate reports of cases of overdose of the preparation of Femara generic. Any specific methods of treating of overdosage are unknown.